1.Heparinisthefirstchoiceforrapidanticoagulation,whichcanbeusedforsurgicalthrombosispreventionandanticoagulationtreatmentinpregnantwomen.Inpatientswithacutemyocardialinfarction,heparincanbeusedtopreve
HeparinsManufacturerintroductionHeparin(includingheparinsodium,heparincalciumandlowmolecularweightheparin)isananticoagulant.Classificationofheparin(1)Ordinary(standard)Heparinisextractedfromthemucousm
1.Oralheparinisineffective.Notsuitableforintramuscularinjection,becauseintramuscularinjectioncancausehematomaattheinjectionsite.Intravenousinjection,intravenousdripanddeepsubcutaneousinjectioncanbeuse
Theanticoagulanteffectofheparinisgenerallythoughttobemainlythroughtwoaspects:①inhibitionofthrombin;②InhibitoryeffectoncoagulationactivefactorXa(FXa).Bothofthemdependonthebindingofthepentosestructure