Heparinsodiumcaninterferewithmanyaspectsofthebloodcoagulationprocessandhasanticoagulanteffectsinvivoandinvitro.Therefore,heparinsodiumcanbeusedforsurgicalpreventionofthrombosisandanticoagulanttreatmen
Themainanticoagulantactionofheparinmainlydependsonantithrombinⅲ.Afterheparinandantithrombinⅲbindthemselves,theconfigurationofantithrombinⅲcandevelopandchange,andcancombinewithavarietyofcoagulationf
1.ConceptandcharacteristicsofchondroitinsulfateChondroitinsulfateisapolysaccharidecomposedofrepeateddisaccharideunitsformedbytheconnectionofD-glucuronicacidandN-acetylgalactosamineviaβ-1,4-glycosidic
Lowmolecularweightheparinisageneraltermforaclassofrelativelylowmolecularweightheparinpreparedbydepolymerizationofcommonheparin.Itwasdevelopedinthe1970sbycombininganewclassofanticoagulantdrugs.Compared