Becauseheparinsodiumhasstrongnegativechargeofphysicalandchemicalcharacteristics,caninterferewithmanyaspectsoftheprocessofbloodcoagulation,invivoandinvitrohaveanticoagulanteffect.Itsmechanismiscomplex,
Enoxaparinsodiumisakindoflowmolecularweightheparinsodium,whichhasthefollowingpharmacologicalactivities:1.Anti-xaactivityLowmolecularweightheparinsodiumMrIsmostlyinagas4~6*103,molecularchainlessthan18s
Chondroitinsulfate(CS)isaclassofglycosaminoglycansthatarecovalentlyattachedtoproteinstoformproteoglycans.Chondroitinsulfateiswidelydistributedintheextracellularmatrixandcellsurfaceofanimaltissues.Thes
1.Heparinsodiumissolubleinwaterandeasytoadd;Addtowaterphase,addatthelaststageofformulation,temperaturelowerthan40℃; 2.ThestabilityofheparinsodiumisbestwhenthepHvalueisbetween7.0and7.5; 3.Lightandanti