Heparinsodiuminterfereswithmanypartsofthebloodcoagulationprocessandhasanticoagulanteffectsinandoutofthebody.Itsmechanismiscomplex,mainlythroughandantithrombinⅢ(AT-Ⅲ),andenhancethelattertoactivateⅡ,
PharmacokineticsAbsorption:Thehalf-lifeofFRAGMINhasbeenshowntobe2hoursafterintravenousinjectionand3-4hoursaftersubcutaneousinjection.Thebioavailabilityaftersubcutaneousinjectionisapproximately90%andth
ACTIONANDCLINICALPHARMACOLOGYMechanismofActionFRAGMINisalowmolecularweightheparinwithantithromboticproperties.Dalteparinsodiumisproducedthroughcontrollednitrousaciddepolymerizationofsodiumheparinfromp
Enoxaparinisusedtopreventandtreatharmfulbloodclots.Thishelpstoreducetheriskofastrokeorheartattack.Thismedicationhelpskeepyourbloodflowingsmoothlybyloweringtheactivityofclottingproteinsintheblood.Enoxa