Heparin sodium has strong anticoagulation and antithrombotic function, that is, antiⅱA and antiXA function. The anticoagulant mechanism of heparin sodium is to inhibit the formation and activity of prothrombin activator and thrombin, thus inhibiting platelet adhesion and aggregation, and indirectly affecting the release of coagulation factors in platelets, so it has anticoagulant effects both in vivo and in vitro.
Heparin sodium also has a variety of biological functions, such as lowering blood lipids, anti-atherosclerosis, anti-media smooth muscle cell proliferation, anti-inflammation, anti-allergy, anti-virus, anti-tumor and so on. Therefore, heparin sodium is widely used in medicine, which is one of the most widely used and most effective anticoagulant drugs in clinical practice. It is mainly used in thromboembolic diseases, myocardial infarction, cardiovascular surgery, cardiac catheterization, extracorporeal circulation, hemodialysis, etc. With the progress of pharmacology and clinical medicine, the scope of application of heparin sodium is still expanding.