The raw material for heparin sodium is crude heparin sodium extracted from the mucosa of the small intestine of healthy pigs. As it contains a large amount of protein, nucleic acid, microorganism and other impurities, physical and chemical extraction and separation process is needed to obtain heparin with complete structure, and then make heparin raw materials. Process flow of heparin sodium: 1. Clean fresh pig lungs with clean water, stir and other related treatment, continue to stir after enzymatic hydrolysis extraction, carry out ion exchange adsorption and other operations, and finally refine the obtained crude heparin sodium.
Heparin sodium is an anticoagulant in vivo and in vitro, and it can also treat bleeding and clotting diseases. Therefore, heparin sodium can participate in and interfere with multiple stages of the clotting process, and can play an anticoagulant role in vivo and in vitro.
The most commonly used heparin sodium in clinic is used for anticoagulation and hemodialysis when intravenous infusion is inserted. It can also be used to prevent embolic diseases, such as pulmonary embolism, myocardial infarction, deep vein thrombosis and postoperative thrombosis. It can also treat diffuse intravascular coagulation caused by a variety of causes, such as placental abruption, sepsis, etc.