Sodium heparin, also known as heparin, is a natural anticoagulant substance containing sulfuric acid mucosaccharides. Heparin sodium is white or white powder, odorless, tasteless, wet, soluble in water, insoluble in ethanol, acetone, dioxane and other organic solvents.
Heparin sodium is widely found in mammalian liver, lung and intestinal mucosa, and most of them are combined with proteins to form a complex. Heparin sodium is a mucopolysaccharide containing sulfuric acid, amino acid and aldose.
Heparin sodium USES:
1, used to delay and obstruct blood clotting.
2, biochemical research, to avoid prothrombin into thrombin.
3. Combined with sodium bicarbonate and sodium lactate, it can promote the anticoagulation effect of sodium heparin.
4. Low molecular weight heparin sodium has obvious and durable antithrombotic effect, and its antithrombotic activity is stronger than anticoagulant activity.
5, biochemical research, used to avoid the conversion of prothrombin into thrombin, has the effect of anti-blood embolism.
Heparin sodium can delay or prevent blood clotting in vitro and in vivo. The mechanism of its effect is complex and affects many links in the process of coagulation. The effect is as follows:
A. Inhibiting the formation and effect of thromboplastin, thereby preventing prothrombin from becoming thrombin;
b. It has the effect of inhibiting thrombin and other coagulation factors at high concentration, and hinders the transformation of fibrinogen into fibrin;
c, can prevent platelet agglutination and damage.