Heparin is one of the most widely used antithrombotic and anticoagulant drugs in clinical practice, and it is the most complex organic compound (mucopolysaccharide sulfate) known to mankind. Firstly, crude heparin is extracted from the small intestine mucosa of fresh healthy pigs and made into crude heparin. Crude heparin is further purified to make heparin API, which is usually in the form of sodium salt and called sodium heparin. In use, heparin sodium is mainly used.

　　Because China is the world's largest producer and butcher of pigs, it is also the world's largest exporter of heparin bulk drugs. According to statistics, China's supply of heparin raw materials accounts for about 50% of the global demand.

　　Crude heparin sodium: from pig intestinal mucosa, through enzymatic hydrolysis process, to get crude heparin, often containing protein or nucleic acid impurities;

　　Heparin API: From crude heparin, it is first purified to form standard heparin. Standard heparin was depolymerized to obtain other low molecular weight heparin apis, such as enoxaparin sodium, natroheparin sodium, dalheparin sodium, etc.

　　Heparin preparation: Divided into standard heparin preparation and low molecular weight heparin preparation.