Heparin sodium is a mucopolysaccharide biochemical drug extracted from porcine small intestinal mucosa with strong anticoagulant activity. Dalteparin belongs to a kind of low molecular weight heparin sodium, which has anticoagulant, antithrombotic, anti-inflammatory, antitumor and inhibitory effects on glomerular mesangial cells and stromal hyperplasia.
Dalteparin is used to prevent the conversion of prothrombin into thrombin, has the effect of anti-blood embolism, and is used to delay and prevent blood coagulation. Dalteparin is the most effective anticoagulant drug with the largest clinical dosage in the world at present, which is mainly used in the treatment of cardiovascular and cerebrovascular diseases and hemodialysis.
Dalteparin has a rapid anticoagulation effect both in vivo and in vitro. It mainly acts on the formation of fibrin and can also reduce platelet aggregation. It can be used to prevent and treat thromboembolic diseases, such as myocardial infarction, pulmonary embolism, cerebrovascular embolism, peripheral venous thrombosis and so on.