Heparin sodium API is mainly used for the production of standard heparin preparation and low molecular weight heparin API, and then the production of low molecular weight heparin preparation. Heparin sodium API can be subdivided into heparin sodium API intermediates and refined heparin sodium API. The purity of heparin sodium API intermediate is relatively low, so it cannot be directly used as standard heparin preparation processing material. The purified heparin sodium API has relatively high purity and complex preparation technology and technology, which is used for the preparation and production of standard heparin preparation and low molecular weight heparin API.
The potency of heparin sodium API is the active unit (IU) contained in heparin sodium API per milligram (mg), and the range of potency required by various countries is generally 150-200IU/mg. From the perspective of heparin sodium API demand, the production of Heparin sodium API in China accounts for 46.47% of the total global demand, and the production of Heparin sodium API in China ranks first in the world.
The role and efficacy of heparin preparation:
1. Treat the early stage of disseminated intravascular coagulation complicated with various diseases.
2, prevention of arteriovenous thrombosis and pulmonary embolism.
3, the treatment of arteriovenous thrombosis and pulmonary embolism, ischemic stroke, unstable angina pectoris (reduce symptoms, prevent myocardial infarction), acute myocardial infarction (prevent early re-infarction and extension of the infarction area, reduce mortality).
4, artificial heart lung, peritoneal dialysis or hemodialysis as anticoagulant drugs.
5. Maintenance treatment as thrombolysis therapy.
6. In vitro anticoagulants such as blood coagulation prevention and blood bank preservation during blood transfusion.