The low molecular weight heparin precursor is heparin, which is extracted from the large intestine of pigs. Heparin sodium and low molecular weight heparin sodium belong to heparin drugs, they belong to the same class of drugs, mainly reflected in theory, clinical application, and safety differences. Therefore, when there are indications for the use of two drugs, they should strictly follow the doctor's advice, so as not to aggravate the disease by using drugs that are not symptomatic.
1. Theoretical aspects: Heparin sodium is a kind of ordinary heparin, while low molecular weight heparin sodium is a kind of heparin formed by the further lysis of ordinary heparin and the reduction of molecular weight, but the main purpose of both are anticoagulant and have a certain role in preventing thrombosis;
2. Clinical application: ordinary heparin, also known as heparin sodium, usually has relatively equal anticoagulant and antithrombotic effects, while low molecular weight heparin sodium can also be effectively applied to anticoagulation, but the drug has relatively better antithrombotic effects than heparin sodium.
3. Safety: The application of heparin sodium is likely to cause increased bleeding in patients, such as skin and mucous membrane bleeding, blood in the stool, oral wall bleeding when brushing teeth, etc. Therefore, the coagulation function needs to be tested every 4-6 hours during the application process, and the dosage of heparin sodium needs to be constantly adjusted according to the coagulation function. And low molecular weight heparin is the ordinary heparin after further refinement, improve income, in keeping all normal anticoagulant effect of heparin sodium at the same time, it is more convenient to use, also do not need to repeatedly test blood coagulation, at the same time as a result of skin mucous membrane bleeding, oral mucosa bleeding, nose bleeding, traces and a series of bleeding risk, much lower than the ordinary heparin sodium.
Caution should be taken when using heparin sodium and low molecular weight heparin sodium, and should be prohibited if allergic to both drugs. At the same time, for patients with severe hypertension and pancreatic lesions, it is also necessary to constrict the use of heparin sodium and low molecular weight heparin sodium. Qingdao Jiulong is a Heparins Manufacturer, affordable price, welcome to consult and understand!