Common heparin sodium and low molecular heparin sodium anticoagulant action distinction?

  Common heparin is a kind of aminoglucan sulfate extracted from pig intestine mucosa or bovine lung. It is a mixture with a molecular weight range of 3000 ~ 30000KD. Low molecular weight heparin is the fragment of amino glucan sulfate after the cracking of ordinary heparin, and it is also a mixture with a molecular weight range of 3000 ~ 5000KD.

  Low Molecular Weight Heparin is a general term for a class of Heparin with Low Molecular Weight prepared by depolymerization of ordinary Heparin. So low molecular weight heparin is actually a general name for a class of drugs, including enoxaparin sodium, natron heparin calcium, Dalteparin and so on.

Common heparin sodium and low molecular heparin sodium anticoagulant action distinction?

  Heparin with higher molecular weight can simultaneously bind to antithrombin ⅲ, coagulation factor ⅹ A and coagulation factor ⅱ A, and play the role of anticoagulation factor ⅹ A and ⅱ A. The binding of low molecular weight heparin with antithrombin ⅲ can increase the affinity between antithrombin ⅲ and coagulation factor ⅹ A, and mainly play the role of anticoagulation factor ⅹ A.