What are the precautions for Enoxaparin sodium?

  Enoxaparin sodium is mainly used to prevent venous thrombosis after plastic surgery and general surgery and clotting during cardiopulmonary bypass during hemodialysis. Prevention of deep vein thrombosis and pulmonary embolism, treatment of existing deep vein thrombosis.

  1. Abnormal liver function; Patients with uncontrolled hypertension; Patients with a history of gastrointestinal ulcer; It is forbidden for nursing women.

  2. Enoxaparin sodium should not be mixed with other injections or intravenous fluids.

  3. The ideal site for injection is the subcutaneous tissue in the center of the anterior or dorsal abdominal wall while the patient is in bed. The injection should be carried out alternately from left to right. Do not push or pull the injection piston before injection to avoid inaccurate dose or hematoma at the injection site.

What are the precautions for Enoxaparin sodium?

  4. An overdose can cause bleeding. It can be neutralized with protamine. Protamine 1mg can neutralize the effect of enoxaparin sodium 1mg anticoagulant factor ⅱ a. High doses of protamine could not completely neutralize anticoagulant factor ⅹ A (up to 60%), but retained its antithrombotic effect.

  5. Enoxaparin sodium should not be intramuscular. Enoxaparin sodium used during intrathecal/epidural anesthesia can cause long-term or permanent paralytic spinal cord bleeding, and the risk is increased due to the epidural catheter after surgery. Patients are carefully monitored to prevent spinal cord and epidural bleeding and immediately discontinue medication if neurological dysfunction is detected.

  6. As different LMWH are not equivalent, different products are not used in the same course of treatment.

  7. Enoxaparin sodium should not be used for more than 24 hours after opening the bottle.