Heparins Manufacturer introduction Heparin sodium is an anticoagulant, which has strong physical and chemical properties of negative charge, can interfere with many links of blood coagulation, and has anticoagulant effect in vivo and in vitro. The anticoagulant mechanism is quite complex, mainly through the combination of antithrombin, which can inhibit the activated clotting factors to some extent. It prevents platelet aggregation and destruction, the formation of thrombin and the conversion of prothrombin to thrombin. In addition, it inhibits thrombin, thereby preventing the conversion of fibrinogen to fibrin, which is anticoagulant in many ways.
The clinical indications for heparin sodium from the Heparins Manufacturer are described as follows:
1. Prevent thrombosis and embolism, such as deep vein thrombosis, myocardial infarction, pulmonary embolism, thrombophlebitis and postoperative thrombosis.
2. Treat DIC caused by various causes of disseminated intravascular coagulation, such as bacterial septicemia, placental abruption, and lysis of malignant tumor cells, except DIC caused by snake bite. Early application prevents the depletion of fibrinogen and other clotting factors.
3, other in vitro and in vivo anticoagulant drugs, such as cardiac catheterization, cardiac surgery, extracorporeal circulation, hemodialysis, etc. Heparin sodium is considered for treatment in these areas. Medication must be administered according to symptoms on the advice of a doctor.