Heparin sodium is commonly used in tablets, creams, injections and other anticoagulant drugs. Heparin sodium injection is mainly used to prevent thrombosis, myocardial infarction, thrombophlebitis, pulmonary embolism, etc. There are also various causes of disseminated intravascular coagulation; At the same time, it is also used in hemodialysis, extracorporeal circulation, catheterization, microvascular surgery and other operations and some blood specimens or instruments for anticoagulation treatment. And heparin sodium lozenges used to prevent cerebral thrombosis, arterial thrombosis. Heparin sodium cream for early chilblain, chap, ulcer, eczema and superficial phlebitis and soft tissue injury, different types of heparin sodium use will be different
Heparin Sodium API Supplier adverse reactions to Heparin Sodium
Heparin sodium injection:
1, low toxicity, the adverse reaction is excessive medication can cause spontaneous bleeding, so the coagulation time should be measured before injection. If severe bleeding occurs after injection, protamine sulfate can be injected intravenously for first aid (1mg protamine sulfate neutralizes 150U of heparin). Heparin sodium injection can occasionally cause allergic reactions and thrombocytopenia, which usually occur within the first 5-9 days of administration. Therefore, platelet count should be monitored regularly within 1 month of the beginning of treatment.
2. One-off hair loss and diarrhea can also occur. It can also cause osteoporosis and spontaneous fractures. Long-term use of antithrombin ⅲ in patients with liver dysfunction will cause the tendency of thrombosis, so more attention should be paid to the use.
Adverse reactions of Heparin sodium lobuccal tablet: a few patients may have allergic reactions such as fever, rash, pruritus, associated membrane inflammation, asthma, precardiac urgency and shortness of breath. Transient alopecia, diarrhea, osteoporosis and spontaneous fractures may also occur, and thrombosis may occur during long-term use, possibly as a result of antithrombin ⅲ exhaustion.
Adverse reactions to heparin sodium cream are rare skin irritation, such as burning sensation, or allergic reactions, such as rash, itching, etc.