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Heparins Manufacturer: Process for salting heparin sodium!

  The diluted mucosa was pumped into the reaction tank using a cutting pump, and the ph was adjusted from 8.3 to 8.8, and the salinity was adjusted from 4.5 to 5.3 degrees by the Beaumeter. Heat to 55 ° C and keep warm for 2 hours at PH8.3-8.8. Heat it up to 90 degrees. Let stand for 15 minutes to remove the residue. Discharge filter residue filtrate body. The liquid was pumped into the adsorption tank, cooled to 53-58 degrees, adjusted ph8.3 to 8.8, and put in resin adsorption. 5-12 hours later, the adsorbent is discharged and the resin is collected by filtration.

  Waste water is discharged into the sewage treatment system. After the resin is cleaned, drip dry (stir with 5% brine for 30 minutes and drain brine). Heat with saturated brine to 55 degrees in the elution tank and stir for 4 hours, 3 hours, 2 hours, 1 hour.

Heparins Manufacturer: Process for salting heparin sodium!

  Heparins Manufacturer: Process for salting heparin sodium

  Filter and collect the first and second eluents, mix them, and use the third and fourth eluents as the first and second eluents of the next time; Add about twice the volume of ethanol into the first and second mixtures, stir evenly, and let stand for more than 15 minutes.

  Siphon off the supernatant and get the wet crude heparin sodium below. Filter dripping wet and dry products; The wet product is placed in the container with more than 5 times the amount of high ethanol twisted loose dehydration for more than 15 minutes; Collect and control dry and wet ethanol; Put the crude wet heparin sodium into the oven of no higher than 60 degrees for drying; Collect dried heparin sodium and store sealed for sale.