As an anticoagulant, heparin sodium has an effect on many links of the coagulation process and can prolong the coagulation time and prothrombin time. This product, whether in vivo or in vitro, has a rapid anticoagulant effect, mainly in the formation of fibrin, but also can reduce platelet aggregation.
This product can be used for the prevention and treatment of thromboembolic diseases, such as myocardial infarction, pulmonary embolism, cerebrovascular embolism, peripheral venous thrombosis, etc., can prevent the formation and expansion of thrombosis, can also be used for the early stage of DIC, and other in vivo and in vitro anticoagulation. Early use can prevent fibrinogen and coagulation factor depletion, and can also be used as an in vitro anticoagulant in blood transfusion or cardiopulmonary bypass.
Cerebrovascular disease is the number one killer of human diseases. With the improvement of people's living standard, it leads to the over-nutrition, the deterioration of the global environment, the acceleration of the pace of life, the aggravation of the aging of the population, and the worldwide incidence and mortality of cardiovascular and cerebrovascular diseases are increasing year by year. The emergence of heparin has created a miracle of life for many patients with cardiovascular and cerebrovascular diseases.
At present, heparin is the most effective and clinically used anticoagulant drug in the world, mainly used for the treatment of cardiovascular and cerebrovascular diseases and hemodialysis, among which heparin is the only effective specific drug in hemodialysis treatment. Clinical applications and studies have shown that heparin has a variety of other biological activities and clinical uses in addition to anticoagulation, including the effect of lowering blood lipid, anti-SMC proliferation, promoting fibrinolysis and other effects. In addition, low molecular weight heparin is a large class of antithrombotic drugs, is further processed from heparin raw materials, has a wide range of clinical applications, has become the treatment of acute venous thrombosis and acute coronary syndrome (angina, myocardial infarction) preferred drugs.
Heparin is the most complex compound in molecular structure known in the world, which cannot be synthesized artificially in a short time. At present, only heparin from pig intestinal mucosa can be used clinically.
Heparin Sodium API Supplier The raw material of heparin API is crude heparin, which can only be extracted from the small intestinal mucosa of healthy pigs. Due to the large amount of impurities such as protein, nucleic acid, microorganism and so on, physical and chemical extraction and separation processes are needed to obtain heparin with complete natural structure and groups, thus making heparin API. Heparin sodium is the only active ingredient in standard heparin preparations and is the starting point for the production of low molecular weight heparin raw materials.