Heparin is an anticoagulant that includes heparin sodium, heparin calcium, and low molecular weight heparin.
Classification of heparin
(1) Ordinary (standard) heparin is extracted from pig or sheep mucosa with an average molecular weight of 15,000, which is quite stable.
(2) The general molecular weight less than 6000 is called low molecular weight heparin. Compared with ordinary heparin, low molecular weight heparin has a longer half-life and better antithrombotic effect, but it has a weak tendency to anticoagulant bleeding and has a tendency to replace ordinary heparin. In recent years, the commonly used clinical drugs include bataria sodium, enoxaparin sodium and low molecular weight heparin calcium.
(3) Currently, there are heparin with low anticoagulant activity, modified heparin, heparin, etc. It has the characteristics of low anticoagulation, high antithrombus, long action time and less bleeding, and has a great development prospect.
Heparin sodium: This product is a sodium salt of glucosamine sulfate extracted from pig intestinal mucosa. It is the main substance of mucosaccharide and plays an anticoagulant role through the systematic activation of antithrombin Ⅲ(at-at). It plays an important role in promoting the three development stages of coagulation function process for students. It has anticoagulant effect in both the in vivo and in the external environment, and can prolong the coagulation response time, prothrombin activity time and thrombin time of patients. It is not absorbed orally and is well absorbed subcutaneously, muscularly or intravenously.
Heparin calcium and heparin sodium have similar therapeutic effects, but this product through the subcutaneous tissue injection does not reduce the cause of intercellular capillaries of calcium glia, also does not change and blood vessels have permeability, basically overcome the side effect of heparin sodium subcutaneous injection is easy to cause bleeding. It may also have a significant antirenin and antialdosterone activity.
The above is the classification and characteristics of Heparin, want to know about Heparin Sodium Price, welcome to consult and understand!