Heparin sodium can interfere with many aspects of the blood coagulation process and has anticoagulant effects in vivo and in vitro. 2. Heparin sodium: After first and antithrombin Ⅲ (AT - Ⅲ), and enhance the latter to activate Ⅱ, Ⅸ, X, Ⅺ and hallooing Ⅻ clotting factors, the result involves blocking platelet aggregation and damage, prevent blood coagulation activation enzyme composition, blocking prothrombin into thrombin, bay thrombin, then block fibrinogen to fibrin, then play a role of anticoagulation.
Heparin sodium crude products:
1. Heparin is a polysaccharide biochemical substance extracted from the mucous membrane of the small intestine of pigs. It is called "heparin sodium" because it is usually in the form of sodium salt. Heparin has strong anticoagulant and antithrombotic functions, and is mainly used for anticoagulant and antithrombotic treatment in clinical practice. It is also the raw material for the production of drugs such as low molecular weight heparin.
Drug category: Anticoagulant and thrombolytic drugs
2. [Properties] This product is colorless or light yellow clear liquid.
3, the functions and indications 】 this product is used for the prevention and treatment of thrombosis or embolism disease (such as myocardial infarction, thrombophlebitis, pulmonary embolism, etc.), various causes of diffuse intravascular coagulation (DIC), also used in hemodialysis, extracorporeal circulation, catheter, such as microvascular surgery operation and some blood specimens or instrument of anticoagulant treatment.
4. Pharmacology and toxicology: due to the physical and chemical properties of this product with strong negative charge, it can interfere with many links of the blood coagulation process and has anti-coagulation effect in vivo and in vitro. The mechanism of its action is complex, mainly through the combination of antithrombin Ⅲ (AT-ANA), and enhance the inhibition of activated Ac, C, C, V and existing coagulation factors by the latter. Its consequences involve preventing platelet agglutination and destruction and inhibiting the formation of thromboactivase; Prevent prothrombin from becoming thrombin; Inhibits thrombin, thereby preventing fibrinogen from becoming fibrin.
The above is the introduction of Heparins Manufacturer's crude heparin sodium products, which I hope will help you better understand heparin sodium.