Dermosin sulfate (DS), as a disaccharide polymer, is the most widely
distributed extra cell Ularmatrix (ECM) glycosaminoglycan in animals, and is the
main component of proteoglycan in blood vessel wall.
DS is a glycosaminoglycan consisting of a polysaccharide consisting of a repeating disaccharide unit of D-glucuronic acid and N-acetylgalactose linked by -1, 4-glucoside bonds and sulfated on the C-4 or C-6 hydroxyl of N-acetylgalactose.
Due to the presence of sulfate group, the entire CS molecule is highly electronegative and easily covalently combined with proteins to form proteoglycans, which are also the important basis for its biological function. As an important part of connective tissue, DS has a variety of pharmacological and physiological functions and can be used as medicine and health food, mainly for osteoarthritis (OA) and coronary atherosclerotic heart disease (CORONARY heart disease).