Chondroitin sulfate (chondroitinsulfate, CS) is a kind of sulfating sugar
glycosaminoglycans, exists in human and animal connective tissue, mainly
distributed in cartilage, bone, tendon, muscle membrane and blood vessel walls,
by D - glucuronic acid and N - acetyl amino galactose with 1, 3 - D - glycosidic
bond connection form the disaccharide, disaccharide connection to beta 1, 4
glycosidic bond, relative molecular mass (Mr) is 25000 ~ 30000.
According to the difference in the glucuronic acid type and the position of sulfate on the hexosamine in their molecular structure, they are mainly divided into chondroitin A(CS-A), chondroitin C(CS-C), chondroitin D(CS-D), and chondroitin E(CS-E), etc. In Europe, the United States, Japan and other countries, CS is mainly used as health food or medicine for the prevention and treatment of cardiovascular and cerebrovascular diseases, osteoarthritis, nerve protection and so on.
CS has anti-inflammatory, immune regulation, protection of heart head blood-vessel, nerve protection, anti-oxidation, cell adhesion control, a variety of pharmacological activities such as anti-tumor, and long-term use of side effects, small is an important biochemical drugs, in against parasites and virus infection, tissue repair, antitumor, and as drug carrier have potential applications in such fields as development prospect.