Follicle stimulating hormone a hormone secreted by basophil cells in the anterior pituitary gland and composed of glycoproteins. The main function is to promote follicular maturation. Human follicle stimulating hormone promotes follicle granulosa cell proliferation and differentiation, promoting the growth of the entire ovary. Acting on testicular convoluted spermatozoa can promote sperm formation. FSH injection only increased the number of follicles and had no effect on follicular maturation. The hypothalamus secretes a follicle-stimulating hormone releasing hormone that controls the secretion of follicle-stimulating hormone. During the menstrual cycle, the blood concentration of FSH and the daily amount of FSH excreted by the urine vary with the cycle. After menopause, the amount of FSH excreted in blood and urine increases.
Secretory feedback regulation
In women, follicle stimulating hormone is closely related to ovulation, and its level is a direct response to the state of ovarian function. The pituitary gland secretes follicle stimulating hormone, which circulates through the blood to the ovaries, stimulating follicle growth and participating in follicle recruitment. In menstrual cycle 2-3 days begin to secrete, pulsed release, about once every minute secretion peak, stimulate follicle growth, and make the particles within the follicle cells grow mature, secrete estrogen, part of estrogen to enter blood circulation, the hypothalamus and pituitary gland produces feedback to the low concentration of estrogen, more follicle-stimulating hormone secretion, stimulate the granular cell, make estrogen secretion increased, eventually reached the peak before ovulation, start the LH secretion, trigger ovulation. Peak estrogen levels suppress follicle stimulating hormone secretion by the pituitary gland and begin the luteal phase of the ovary, where follicle stimulating hormone levels gradually decrease until the menstrual period reaches the baseline and the next secretory cycle begins.