Heparin sodium has a strong anticoagulant effect, which is commonly used as a systemic anticoagulant in animals when performing experiments such as death resuscitation. The anticoagulant effect of heparin sodium is mainly to inhibit the activity of thromboplastin, prevent platelet aggregation and inhibit antithrombin, so as to prevent blood coagulation. Moving principle of heparin anticoagulant heparin is a kind of groups containing sulfate glycosaminoglycan, with a strong negative charge, through the combined with antithrombin 3, enhance the effect of antithrombin, inactivated serine protease, which has prevented thrombin formation are activated to restrain activity of thrombin and preventing platelet aggregation and so on the many kinds of anticoagulation, prevent blood clots.

　　Why should heparin be used for anticoagulation when hemodialysis?

　　Hemodialysis is actually a kind of extracorporeal circulation therapy. Anticoagulants must be used to prevent coagulation during cardiopulmonary bypass, which is a necessary guarantee for the smooth progress of hemodialysis. Heparin is the anticoagulant commonly used in hemodialysis.

　　Hemodialysis is actually a kind of extracorporeal circulation therapy. Anticoagulants must be used to prevent coagulation during cardiopulmonary bypass, which is a necessary guarantee for the smooth progress of hemodialysis. Heparin is the anticoagulant commonly used in hemodialysis.