1. Heparin: Heparin, now named after its 5261 origins from the liver, is composed of glucosamine, 4102L-adosaccharide, N-acetylgluc1653 glucosamine and D-glucuronic acid alternately, with an average molecular weight of 15KD.
2. Heparin sodium: Heparin sodium can interfere with many links of the hemagglutination process, and has anticoagulant effect both in vivo and in vitro.
3. Heparin calcium: a drug used in hemodialysis to prevent blood clots.
Second, the purpose
1. Heparin: Clinically, it is mainly used for thromboembolic diseases, myocardial infarction, cardiovascular surgery, cardiac catheterization, cardiopulmonary bypass, hemodialysis, etc.
2. Heparin sodium: prevent thrombosis and embolism, treat disseminated intravascular coagulation (DIC) caused by various causes, and other in vivo and in vitro anticoagulants.
3. Heparin calcium: prepare anticoagulant and thrombotic drugs.
1. Heparin: It is strongly acidic and exists in lungs, blood vessel walls, intestinal mucosa and other tissues. It is a natural anticoagulant substance in animals. Hygroscopicity, sodium salts that can be stored at room temperature for at least 12 months.
2, mainly through heparin: and antithrombin Ⅲ (AT - Ⅲ), and enhance the latter to activate Ⅱ, Ⅸ, X, Ⅺ and Ⅻ the inhibitory effect of clotting factors and its consequences involved in preventing platelet aggregation and destruction, inhibit the formation of blood coagulation activation of enzyme, blocking prothrombin into thrombin, inhibition of thrombin, thereby preventing fibrinogen to fibrin, which play a role of anticoagulation.
3. Heparin calcium: Heparin calcium is an amorphous powder. Insoluble in ethanol, acetone and other organic solvents.