Usage and dosage of heparin sodium
1) unstable angina pectoris and non-st-segment elevation myocardial infarction: subcutaneous injection of 120 units /kg(maximum dose of 10,000 units), 2 times a day, lasting for 5-8 days or until the condition is stable, and aspirin at the same time; For patients with delayed interventional therapy, 5000 units (female weight <80kg, male <70kg) or 7500 units of subcutaneous injection were administered, 2 times a day.
2) prevention of deep vein thrombosis after surgery: 2,500 units were injected subcutaneously 1 to 2 hours before surgery, 2,500 units were injected subcutaneously 12 hours after surgery, and then 2,500 units were injected subcutaneously once a day for 5 to 10 days until the patient could move.
3) prevent coagulation during hemodialysis and hemofiltration: for patients with chronic renal failure without known risk of bleeding, if hemodialysis and hemofiltration do not exceed 4 hours, 5000 units of rapid intravenous injection; For more than 4 hours, 30 ~ 40 units /kg was injected intravenously, followed by intravenous infusion at 10 ~ 15 units /kg per hour. Rapid intravenous injection of 5 ~ 10 units /kg for patients with acute renal failure at high risk of bleeding. Patients undergoing hemodialysis with short treatment intervals should be fully monitored against Xa, and the plasma concentration should be kept within the range of 0.2 ~ 0.4 anti-xa /ml.
4) treatment of acute deep vein thrombosis: subcutaneous injection of 200 units /kg, once a day, with a daily dose not exceeding 18,000 units. Patients with a high risk of bleeding may also receive 100 units /kg twice a day.