Heparins Manufacturer

Dheparin sodium injection drug overdose

  Protamine can inhibit the anticoagulant effect of dheparin sodium. The prolongation of clotting time induced by this product can be completely neutralized, but the anti-xa activity is only moderate to about 25-50%. 1 mg protamine can inhibit the anti-xa effect of 100 IU of heparin sodium (low molecular weight heparin sodium). Protamine itself inhibits initial hemostasis and should only be used in emergency situations.